Morganella morganii is a facultative Gram-negative anaerobe present in the human gastrointestinal system as normal flora. Clinically, the organism is important when it manifests as an opportunistic pathogenic infection elsewhere in the body. This paper reviews an unusual case in which M. morganii is the pathogen responsible for a devastating postoperative infection in a diabetic patient. Currently, there are no known reported cases in the literature of M. morganii as an etiologic pathogen for a postoperative foot infection. Prompt diagnosis and treatment of this organism is imperative to reduce the patient's overall morbidity and mortality.