Treatment of nontuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin

J Pediatr. 1996 Mar;128(3):383-6. doi: 10.1016/s0022-3476(96)70288-3.

Abstract

Treatment with clarithromycin plus rifabutin in children with nontuberculous mycobacterial lymphadenitis was associated with resolution of chronic sinus formation and discharge after incomplete excision in five of five cases, and involution of the enlarged lymph nodes in two of three cases treated without surgery.

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Anti-Bacterial Agents / adverse effects
  • Antibiotics, Antitubercular / administration & dosage*
  • Antibiotics, Antitubercular / adverse effects
  • Child, Preschool
  • Clarithromycin / administration & dosage*
  • Clarithromycin / adverse effects
  • Drug Therapy, Combination / adverse effects
  • Drug Therapy, Combination / therapeutic use
  • Female
  • Humans
  • Infant
  • Lymph Node Excision
  • Male
  • Mycobacterium avium-intracellulare Infection / drug therapy*
  • Mycobacterium avium-intracellulare Infection / surgery
  • Prospective Studies
  • Rifabutin / administration & dosage*
  • Rifabutin / adverse effects
  • Tooth Discoloration / chemically induced
  • Tuberculosis, Lymph Node / drug therapy*
  • Tuberculosis, Lymph Node / surgery

Substances

  • Anti-Bacterial Agents
  • Antibiotics, Antitubercular
  • Rifabutin
  • Clarithromycin