Pneumonia caused by Nocardia nova and Aspergillus fumigatus after cardiac transplantation

Eur J Clin Microbiol Infect Dis. 1993 Feb;12(2):112-4. doi: 10.1007/BF01967585.

Abstract

Nocardia nova, a newly established species of the Nocardia asteroides complex, has recently been characterized as a human pathogen. This report of a case of pneumonia caused by Nocardia nova and Aspergillus fumigatus in a patient after cardiac transplantation is the first reported infection caused by Nocardia nova following its detailed description. Accurate identification and susceptibility testing of the Nocardia nova isolate allowed successful oral therapy with clarithromycin when therapy with sulfisoxazole was not tolerated.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Aspergillosis / complications
  • Aspergillosis / drug therapy
  • Aspergillosis / microbiology*
  • Aspergillus fumigatus / isolation & purification*
  • Bronchoalveolar Lavage Fluid / microbiology
  • Clarithromycin / therapeutic use
  • Drug Therapy, Combination
  • Heart Transplantation*
  • Humans
  • Immunocompromised Host
  • Lung Diseases, Fungal / complications
  • Lung Diseases, Fungal / drug therapy
  • Lung Diseases, Fungal / microbiology
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Nocardia / drug effects
  • Nocardia / isolation & purification
  • Nocardia Infections / complications
  • Nocardia Infections / drug therapy
  • Nocardia Infections / microbiology*
  • Pneumonia / drug therapy
  • Pneumonia / microbiology*
  • Postoperative Complications / drug therapy
  • Postoperative Complications / microbiology
  • Sulfisoxazole / adverse effects
  • Sulfisoxazole / therapeutic use

Substances

  • Sulfisoxazole
  • Amphotericin B
  • Clarithromycin