Ceftriaxone no longer predictably cures chancroid in Kenya

J Infect Dis. 1993 Feb;167(2):469-71. doi: 10.1093/infdis/167.2.469.

Abstract

Ceftriaxone in a dose of 250 mg given intramuscularly is currently recommended for the treatment of chancroid. Among 133 men in Nairobi, Kenya, with culture-proven chancroid, who were treated with ceftriaxone, treatment failed in 35%. Poor outcome was associated with human immunodeficiency virus type 1 seropositivity. Thus, treatment recommendations for chancroid should be reevaluated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Ceftriaxone / therapeutic use*
  • Chancroid / complications
  • Chancroid / drug therapy*
  • Follow-Up Studies
  • HIV Seropositivity / complications*
  • HIV-1 / immunology*
  • Humans
  • Kenya
  • Male
  • Treatment Outcome

Substances

  • Ceftriaxone