Comparative efficacy of two- and five-day courses of ceftriaxone for treatment of severe shigellosis in children

J Pediatr. 1993 Nov;123(5):822-4. doi: 10.1016/s0022-3476(05)80868-6.

Abstract

Administration of ceftriaxone for 5 days has been shown to be highly efficient in the treatment of severe shigellosis in children. Our study, involving 40 children, demonstrated that a 2-day course of ceftriaxone was as beneficial as a 5-day course and constituted effective therapy for children with severe shigellosis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Ceftriaxone / administration & dosage*
  • Ceftriaxone / therapeutic use
  • Child
  • Child, Preschool
  • Diarrhea, Infantile / drug therapy
  • Diarrhea, Infantile / microbiology
  • Dose-Response Relationship, Drug
  • Dysentery, Bacillary / drug therapy*
  • Humans
  • Infant
  • Shigella flexneri
  • Shigella sonnei*
  • Treatment Outcome

Substances

  • Ceftriaxone