Antiemetic-induced akathisia in cancer patients receiving chemotherapy

Am J Psychiatry. 1994 May;151(5):763-5. doi: 10.1176/ajp.151.5.763.

Abstract

A structured, prospective telephone interview was used to assess the prevalence of akathisia in 24 cancer patients receiving metoclopramide or prochlorperazine during or after chemotherapy. Half of the patients reported subjective motor restlessness, and 75% stated that they would not have informed staff. This report suggests that akathisia is frequently unrecognized in chemotherapy patients receiving metoclopramide and prochlorperazine.

MeSH terms

  • Akathisia, Drug-Induced / epidemiology*
  • Akathisia, Drug-Induced / etiology
  • Antineoplastic Agents / adverse effects
  • Drug Therapy, Combination
  • Female
  • Humans
  • Male
  • Metoclopramide / adverse effects*
  • Metoclopramide / therapeutic use
  • Middle Aged
  • Nausea / chemically induced
  • Nausea / prevention & control
  • Neoplasms / drug therapy*
  • Prochlorperazine / adverse effects*
  • Prochlorperazine / therapeutic use
  • Prospective Studies
  • Surveys and Questionnaires
  • Telephone
  • Vomiting / chemically induced
  • Vomiting / prevention & control

Substances

  • Antineoplastic Agents
  • Metoclopramide
  • Prochlorperazine