Abstract
The activity of DU-6859a, a new fluoroquinolone antimicrobial agent, was compared with that of ciprofloxacin by agar dilution susceptibility testing against enteric pathogens and multiresistant Escherichia coli. The results indicate that DU-6859a inhibits most of these organisms at concentrations similar to those of ciprofloxacin. DU-6859a showed increased activity compared to ciprofloxacin against Campylobacter species isolates.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Infective Agents / pharmacology*
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Ciprofloxacin / pharmacology
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Diarrhea / drug therapy
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Drug Resistance, Multiple
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Escherichia coli
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Fluoroquinolones*
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Gram-Negative Bacteria / drug effects*
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Humans
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In Vitro Techniques
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Microbial Sensitivity Tests
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Quinolones / pharmacology*
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Spiro Compounds / pharmacology*
Substances
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Anti-Infective Agents
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Fluoroquinolones
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Quinolones
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Spiro Compounds
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Ciprofloxacin
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sitafloxacin