DU-6859a, a new fluoroquinolone agent. Comparative in vitro activity against enteric pathogens and multiresistant outpatient Escherichia coli

Diagn Microbiol Infect Dis. 1994 Sep;20(1):45-7. doi: 10.1016/0732-8893(94)90018-3.

Abstract

The activity of DU-6859a, a new fluoroquinolone antimicrobial agent, was compared with that of ciprofloxacin by agar dilution susceptibility testing against enteric pathogens and multiresistant Escherichia coli. The results indicate that DU-6859a inhibits most of these organisms at concentrations similar to those of ciprofloxacin. DU-6859a showed increased activity compared to ciprofloxacin against Campylobacter species isolates.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / pharmacology*
  • Ciprofloxacin / pharmacology
  • Diarrhea / drug therapy
  • Drug Resistance, Multiple
  • Escherichia coli
  • Fluoroquinolones*
  • Gram-Negative Bacteria / drug effects*
  • Humans
  • In Vitro Techniques
  • Microbial Sensitivity Tests
  • Quinolones / pharmacology*
  • Spiro Compounds / pharmacology*

Substances

  • Anti-Infective Agents
  • Fluoroquinolones
  • Quinolones
  • Spiro Compounds
  • Ciprofloxacin
  • sitafloxacin