[Evaluation of the potential of chemotherapy of glanders caused by Pseudomonas mallei strains resistant to sulfanilamides and trimethoprim]

Antibiot Khimioter. 1994 Jul;39(7):30-4.
[Article in Russian]

Abstract

A sulfanilamide resistant strain Ts-5 of Pseudomonas mallei was isolated in the experiments on sulfazine therapy of malleus. The spectrum and level of the strain cross resistance to sulfanilamides and trimethoprim were studied. The frequency of the SurTrr mutants of P. mallei was determined. Efficient antibacterial drugs for the therapy of malleus caused by the sulfanilamide resistant strain are recommended.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Cricetinae
  • Drug Resistance, Multiple / physiology*
  • Evaluation Studies as Topic
  • Glanders / drug therapy*
  • Mesocricetus
  • Pseudomonas / drug effects*
  • Sulfanilamides / therapeutic use*
  • Trimethoprim Resistance / physiology*

Substances

  • Sulfanilamides