Abstract
The susceptibility of 26 isolates of Nocardia asteroides to several antibiotics was determined by the agar dilution technique. Many currently available beta-lactam antibiotics were ineffective. Cefotaxime, cefmenoxime, and N-formimidoyl thienamycin were active against these strains, with 80% minimal inhibitory concentrations of 4, 4, and 2 micrograms/ml, respectively. Amikacin was the most effective agent tested.
MeSH terms
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Amikacin / pharmacology
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Anti-Bacterial Agents / pharmacology*
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Drug Combinations / pharmacology
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Imipenem
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Microbial Sensitivity Tests
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Nocardia asteroides / drug effects*
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Sulfamethoxazole / pharmacology
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Trimethoprim / pharmacology
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Trimethoprim, Sulfamethoxazole Drug Combination
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beta-Lactams / pharmacology
Substances
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Anti-Bacterial Agents
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Drug Combinations
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beta-Lactams
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Imipenem
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Trimethoprim, Sulfamethoxazole Drug Combination
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Amikacin
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Trimethoprim
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Sulfamethoxazole