Tularemia complicated by acute renal failure

South Med J. 1983 Feb;76(2):273-4. doi: 10.1097/00007611-198302000-00041.

Abstract

Acute renal failure has been a rare, uniformly fatal complication of infection with Francisella tularensis. The literature suggests that either acute tubular necrosis, interstitial nephritis, or glomerulonephritis may be responsible for this syndrome. We have described a patient with tularemia who had nonoliguric acute renal failure probably due to interstitial nephritis and who recovered slowly but spontaneously during antimicrobial therapy with doxycycline.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acute Kidney Injury / drug therapy
  • Acute Kidney Injury / etiology*
  • Aged
  • Cerebrospinal Fluid / analysis
  • Doxycycline / therapeutic use
  • Humans
  • Male
  • Nephritis / drug therapy
  • Nephritis / etiology
  • Tularemia / complications*
  • Tularemia / diagnosis
  • Tularemia / immunology

Substances

  • Doxycycline