Susceptibility of gram-positive cocci to various antibiotics, including cefotaxime, moxalactam, and N-formimidoyl thienamycin

Antimicrob Agents Chemother. 1981 Oct;20(4):553-5. doi: 10.1128/AAC.20.4.553.

Abstract

The activities of cefotaxime, moxalactam, MK 0787 (N-formimidoyl thienamycin), ampicillin, oxacillin, vancomycin, and clindamycin were compared against gram-positive cocci. MK 0787 was the most active and moxalactam was the least active of these drugs, except against methicillin-resistant Staphylococcus aureus, where vancomycin was most active, and penicillin-resistant pneumococci, where cefotaxime was more active.

Publication types

  • Comparative Study

MeSH terms

  • Ampicillin / pharmacology
  • Anti-Bacterial Agents / pharmacology*
  • Cefotaxime / pharmacology*
  • Cephalosporins / pharmacology*
  • Cephamycins / pharmacology*
  • Imipenem
  • Lactams / pharmacology
  • Microbial Sensitivity Tests
  • Moxalactam
  • Oxacillin / pharmacology
  • Staphylococcus / drug effects*
  • Staphylococcus aureus / drug effects
  • Streptococcus / drug effects*
  • Streptococcus pneumoniae / drug effects

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Cephamycins
  • Lactams
  • Imipenem
  • Ampicillin
  • Cefotaxime
  • Oxacillin
  • Moxalactam