Candida epiglottitis in immunocompromised patients

Chest. 1987 Apr;91(4):482-5. doi: 10.1378/chest.91.4.482.

Abstract

Candida seldom has been reported to be a cause of epiglottitis. The clinical manifestations and management of three patients with Candida epiglottitis complicating their neoplastic disease are described. All patients were granulocytopenic. Candida epiglottitis occurred either as a localized infection, as a source of Candida bronchopneumonia, or as a manifestation of disseminated infection. Candida epiglottitis may be under-diagnosed and should be considered, especially in immunocompromised patients with symptoms of refractory pharyngitis. Treatment of Candida epiglottitis with intravenous amphotericin B is warranted in patients with sustained granulocytopenia. Prompt endotracheal intubation is indicated if the airway patency cannot be maintained.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Agranulocytosis / complications
  • Amphotericin B / therapeutic use
  • Candidiasis / diagnosis
  • Candidiasis / drug therapy
  • Candidiasis / etiology*
  • Child, Preschool
  • Epiglottitis / diagnosis
  • Epiglottitis / drug therapy
  • Epiglottitis / etiology*
  • Female
  • Humans
  • Immunologic Deficiency Syndromes / complications*
  • Intubation, Intratracheal
  • Laryngitis / etiology*
  • Laryngoscopy
  • Male
  • Middle Aged

Substances

  • Amphotericin B