Abstract
We determined the susceptibilities of five strains of Trichomonas vaginalis, one of which was metronidazole resistant, to 50 antimicrobial agents. For the metronidazole-susceptible strains, the most active agents were metronidazole, tinidazole, mebendazole, furazolidone, and anisomycin. Against the resistant strain mebendazole, furazolidone, and anisomycin were the most active. Antifungal agents, beta-lactams, macrolides, aminoglycosides, and folic acid antagonists were ineffective against all strains.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anthelmintics / pharmacology
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Anti-Bacterial Agents / pharmacology
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Anti-Infective Agents / pharmacology*
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Antifungal Agents / pharmacology
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Antiprotozoal Agents / pharmacology
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Drug Resistance
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Folic Acid Antagonists / pharmacology
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Humans
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Metronidazole / pharmacology
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Trichomonas vaginalis / drug effects*
Substances
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Anthelmintics
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Anti-Bacterial Agents
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Anti-Infective Agents
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Antifungal Agents
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Antiprotozoal Agents
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Folic Acid Antagonists
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Metronidazole