Nocardia infection in the acquired immunodeficiency syndrome

Diagn Microbiol Infect Dis. 1989 Nov-Dec;12(6):517-9. doi: 10.1016/0732-8893(89)90086-2.

Abstract

A case of Nocardia asteroides pneumonia in a patient with the acquired immunodeficiency syndrome who was intolerant of sulfadiazine is described. On cefuroxime, the patient had a complete resolution of his Nocardia pneumonia. Disk-diffusion and broth microdilution antibiotic susceptibility testing (MIC less than or equal to 2 micrograms/ml) strongly supported the use of cefuroxime as treatment in this patient. Susceptibility testing with newer cephalosporins should be considered for all significant Nocardia isolates.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Cefuroxime / pharmacology
  • Cefuroxime / therapeutic use*
  • Cephalosporins / therapeutic use*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Nocardia Infections / complications*
  • Nocardia Infections / drug therapy
  • Nocardia asteroides / drug effects
  • Nocardia asteroides / isolation & purification
  • Opportunistic Infections / complications*
  • Opportunistic Infections / drug therapy
  • Pneumonia / complications*
  • Pneumonia / drug therapy
  • Sputum / microbiology
  • Sulfadiazine / adverse effects
  • Sulfadiazine / therapeutic use

Substances

  • Cephalosporins
  • Sulfadiazine
  • Cefuroxime