Antimicrobial Drug Resistance of Vibrio cholerae, Democratic Republic of the Congo

Emerg Infect Dis. 2015 May;21(5):847-51. doi: 10.3201/eid2105.141233.

Abstract

We analyzed 1,093 Vibrio cholerae isolates from the Democratic Republic of the Congo during 1997-2012 and found increasing antimicrobial drug resistance over time. Our study also demonstrated that the 2011-2012 epidemic was caused by an El Tor variant clonal complex with a single antimicrobial drug susceptibility profile.

Keywords: Democratic Republic of the Congo; El Tor variant; MLVA; Vibrio cholerae O1; antimicrobial resistance; bacteria; cholera; clone; whole-genome sequencing.

Publication types

  • Historical Article

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Cholera / drug therapy
  • Cholera / epidemiology*
  • Cholera / history
  • Cholera / microbiology*
  • Democratic Republic of the Congo / epidemiology
  • Disease Outbreaks
  • Drug Resistance, Bacterial*
  • Geography
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Microbial Sensitivity Tests
  • Multilocus Sequence Typing
  • Phylogeny
  • Vibrio cholerae / classification
  • Vibrio cholerae / drug effects*
  • Vibrio cholerae / genetics

Substances

  • Anti-Bacterial Agents