Campylobacter virulence and survival factors

Food Microbiol. 2015 Jun:48:99-108. doi: 10.1016/j.fm.2014.11.017. Epub 2014 Dec 25.

Abstract

Despite over 30 years of research, campylobacteriosis is the most prevalent foodborne bacterial infection in many countries including in the European Union and the United States of America. However, relatively little is known about the virulence factors in Campylobacter or how an apparently fragile organism can survive in the food chain, often with enhanced pathogenicity. This review collates information on the virulence and survival determinants including motility, chemotaxis, adhesion, invasion, multidrug resistance, bile resistance and stress response factors. It discusses their function in transition through the food processing environment and human infection. In doing so it provides a fundamental understanding of Campylobacter, critical for improved diagnosis, surveillance and control.

Keywords: Campylobacter; Foodborne pathogens; Survival; Virulence factors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Campylobacter / genetics
  • Campylobacter / growth & development
  • Campylobacter / metabolism*
  • Campylobacter / pathogenicity
  • Campylobacter Infections / microbiology*
  • Humans
  • Virulence
  • Virulence Factors / genetics
  • Virulence Factors / metabolism*

Substances

  • Bacterial Proteins
  • Virulence Factors