Rothia aeria mitral valve endocarditis complicated by multiple mycotic aneurysms: laboratory identification expedited using MALDI-TOF MS

Infection. 2014 Apr;42(2):419-23. doi: 10.1007/s15010-013-0532-x.

Abstract

Rothia aeria has only rarely been described as a human pathogen. We describe a case of Rothia aeria causing mitral valve endocarditis and multiple mycotic aneurysms, including cerebral mycotic aneurysms. In the case described, early identification of Rothia aeria was achieved using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).

Publication types

  • Case Reports

MeSH terms

  • Actinomycetales Infections / diagnosis*
  • Actinomycetales Infections / drug therapy
  • Actinomycetales Infections / microbiology
  • Actinomycetales Infections / pathology
  • Aneurysm, Infected / diagnosis*
  • Aneurysm, Infected / drug therapy
  • Aneurysm, Infected / microbiology
  • Aneurysm, Infected / pathology
  • Antifungal Agents / therapeutic use
  • Endocarditis, Bacterial / diagnosis*
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / microbiology
  • Endocarditis, Bacterial / pathology
  • Humans
  • Male
  • Micrococcaceae / isolation & purification*
  • Middle Aged
  • Mitral Valve / microbiology
  • Mitral Valve / pathology
  • Mycoses / microbiology
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Treatment Outcome
  • Victoria

Substances

  • Antifungal Agents