Abstract
We retrospectively evaluated 410 patients with coinfection or cocolonization due to vancomycin-resistant (VR) enterococcus (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). The prevalence rate was 19.8%. Risk factors included isolation of VR Enterococcus faecalis and use of linezolid or clindamycin. Inc18-like vanA plasmids were found in 7% of VR E. faecalis isolates and none of the VR E. faecium isolates.
MeSH terms
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Acetamides / therapeutic use
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Aged
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Anti-Bacterial Agents / therapeutic use
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Bacterial Proteins / genetics
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Carbon-Oxygen Ligases / genetics
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Carrier State / epidemiology*
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Carrier State / microbiology*
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Clindamycin / therapeutic use
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Comorbidity
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Enterococcus / drug effects
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Enterococcus / isolation & purification*
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Female
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Gram-Positive Bacterial Infections / epidemiology*
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Gram-Positive Bacterial Infections / microbiology*
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Humans
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Linezolid
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Male
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Methicillin-Resistant Staphylococcus aureus / drug effects
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Methicillin-Resistant Staphylococcus aureus / isolation & purification*
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Middle Aged
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Oxazolidinones / therapeutic use
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Plasmids
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Prevalence
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Retrospective Studies
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Risk Factors
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Vancomycin Resistance*
Substances
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Acetamides
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Anti-Bacterial Agents
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Bacterial Proteins
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Oxazolidinones
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VanA ligase, Bacteria
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Clindamycin
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Carbon-Oxygen Ligases
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Linezolid