Development of imipenem resistance in an Aeromonas veronii biovar sobria clinical isolate recovered from a patient with cholangitis

J Med Microbiol. 2009 Apr;58(Pt 4):451-455. doi: 10.1099/jmm.0.47804-0.

Abstract

Several imipenem-susceptible and -resistant Aeromonas veronii biovar sobria isolates with different morphologies and antimicrobial susceptibilities recovered from bile samples of a patient with cholangitis were analysed. These isolates belonged to the same clone and the imipenem-resistant strains showed overexpression of the imiS gene, encoding a chromosomal carbapenemase. These results should make clinicians aware of the possible emergence of multidrug-resistant A. veronii biovar sobria, perhaps as a consequence of previous treatment of a urinary tract infection with amoxicillin plus clavulanic acid.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aeromonas / classification
  • Aeromonas / drug effects*
  • Aged, 80 and over
  • Anti-Bacterial Agents / pharmacology*
  • Cholangitis / microbiology*
  • Drug Resistance, Bacterial*
  • Female
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / microbiology*
  • Humans
  • Imipenem / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Imipenem