Nocardia niigatensis infection in a kidney transplant recipient

Transpl Int. 2009 May;22(5):583-5. doi: 10.1111/j.1432-2277.2008.00826.x. Epub 2009 Jan 16.

Abstract

This is the first reported case of Nocardia niigatensis infection in an adult kidney transplant recipient. A 57-year-old Asian woman presented with multiple cutaneous abscesses and rapidly growing fungating mass on the left pretibial area for 2 months. She received a cadaveric kidney transplant 4 years previously and was undergoing immunosuppression with prednisolone, cyclosporine and mycophenolate sodium. The microbiological diagnosis was established by isolation of Nocardia from the purulent material expressed from a granule. The strain was identified to the species level by 16S rRNA gene-targeted PCR. The closest match was with N. niigatensis. Antibiotic treatment (trimethotrim-sulfamethoxazole) was continued for 6 months and the skin lesions improved.

Publication types

  • Case Reports

MeSH terms

  • Dermatomycoses / diagnosis*
  • Dermatomycoses / drug therapy
  • Dermatomycoses / microbiology
  • Female
  • Humans
  • Kidney Transplantation / immunology*
  • Middle Aged
  • Nocardia Infections / diagnosis*
  • Nocardia Infections / drug therapy
  • Nocardia Infections / immunology
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use

Substances

  • Trimethoprim, Sulfamethoxazole Drug Combination