Tetracycline resistance in Ureaplasma spp. and Mycoplasma hominis: prevalence in Bordeaux, France, from 1999 to 2002 and description of two tet(M)-positive isolates of M. hominis susceptible to tetracyclines

Antimicrob Agents Chemother. 2008 Feb;52(2):742-4. doi: 10.1128/AAC.00960-07. Epub 2007 Nov 19.

Abstract

Twenty-four of 128 clinical isolates of Mycoplasma hominis and 6 of 276 clinical isolates of Ureaplasma spp. from Bordeaux, France (1999 to 2002), were resistant to tetracycline and harbored the tet(M) gene. For M. hominis, we also found an increase in tetracycline resistance and two tet(M)-positive isolates that were susceptible to tetracyclines.

MeSH terms

  • Amino Acid Sequence
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / metabolism*
  • Base Sequence
  • DNA Transposable Elements
  • France / epidemiology
  • Humans
  • Molecular Sequence Data
  • Mycoplasma Infections / epidemiology
  • Mycoplasma Infections / microbiology
  • Mycoplasma hominis / drug effects*
  • Prevalence
  • Sequence Analysis, DNA
  • Tetracycline Resistance*
  • Tetracyclines / pharmacology*
  • Ureaplasma / classification
  • Ureaplasma / drug effects*
  • Ureaplasma Infections / epidemiology
  • Ureaplasma Infections / microbiology

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • DNA Transposable Elements
  • Tet M resistance protein, Bacteria
  • Tetracyclines

Associated data

  • GENBANK/DQ973625