Ultrasound measurement of gallbladder wall thickening as a diagnostic test and prognostic indicator for severe dengue in pediatric patients

Pediatr Infect Dis J. 2007 Sep;26(9):850-2. doi: 10.1097/INF.0b013e3180619692.

Abstract

Gallbladder wall thickening measured by ultrasound was significantly associated with severe dengue, as well as with hallmark features of thrombocytopenia and elevated hematocrit/hemoconcentration, in children with suspected dengue in Nicaragua. We demonstrate that gallbladder wall thickening serves as a clinically relevant diagnostic test and prognostic indicator of severe dengue in pediatric populations.

Publication types

  • Research Support, N.I.H., Extramural
  • Validation Study

MeSH terms

  • Adolescent
  • Antibodies / blood
  • Child
  • Child, Preschool
  • Dengue / diagnosis
  • Dengue / diagnostic imaging*
  • Dengue Virus / immunology
  • Dengue Virus / isolation & purification
  • Female
  • Gallbladder / diagnostic imaging*
  • Gallbladder / pathology
  • Hospitals, Pediatric
  • Humans
  • Immunoglobulin M / blood
  • Male
  • Nicaragua
  • Prognosis
  • Ultrasonography

Substances

  • Antibodies
  • Immunoglobulin M