Cryptosporidium parvum-associated sclerosing cholangitis in a liver transplant patient

Transpl Infect Dis. 2008 Apr;10(2):133-6. doi: 10.1111/j.1399-3062.2007.00245.x. Epub 2007 Jul 1.

Abstract

Cryptosporidium parvum causes severe long-standing diarrhea in immunocompromised patients. Sclerosing cholangitis caused by C. parvum is a rare complication in transplant recipients. We report herein the presentation of Cryptosporidium-associated cholangitis in an adult liver transplant patient diagnosed by liver biopsy. The patient improved on treatment with azithromycin and paromomycin.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Azithromycin / therapeutic use
  • Cholangitis, Sclerosing / drug therapy
  • Cholangitis, Sclerosing / parasitology*
  • Cryptosporidiosis / complications*
  • Cryptosporidium parvum / pathogenicity*
  • Humans
  • Immunocompromised Host
  • Liver Transplantation / adverse effects
  • Liver Transplantation / immunology*
  • Male
  • Middle Aged
  • Paromomycin / therapeutic use
  • Treatment Outcome

Substances

  • Paromomycin
  • Azithromycin