Abstract
A retrospective cohort study was conducted to determine the relapse rate of penicilliosis marneffei after the discontinuation of itraconazole secondary prophylaxis in 33 HIV-infected patients who received HAART and had CD4 cell counts of 100 cells/mul or greater for at least 6 months. The observed incidence of relapse of penicilliosis marneffei was zero cases per 641 person-months (95% confidence interval 0-0.6 cases per person-month) after a median follow-up of 18 months (range 6-45).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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AIDS-Related Opportunistic Infections / complications
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AIDS-Related Opportunistic Infections / prevention & control*
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Acquired Immunodeficiency Syndrome / drug therapy
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Acquired Immunodeficiency Syndrome / immunology
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Adult
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Antifungal Agents / administration & dosage*
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Antiretroviral Therapy, Highly Active*
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CD4 Lymphocyte Count
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Female
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Follow-Up Studies
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Humans
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Itraconazole / administration & dosage
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Male
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Middle Aged
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Mycoses / complications
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Mycoses / prevention & control*
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Penicillium / isolation & purification*
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Recurrence
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Retrospective Studies
Substances
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Antifungal Agents
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Itraconazole