Implantable cardioverter-defibrillator infection due to Brucella melitensis: case report and review of brucellosis of cardiac devices

Clin Infect Dis. 2007 Feb 15;44(4):e37-9. doi: 10.1086/511079. Epub 2007 Jan 5.

Abstract

We report a case of implantable cardioverter-defibrillator infection due to Brucella melitensis and review 5 previously reported cases of Brucella infection of cardiac devices. Device removal, followed by antibiotic therapy for 6 weeks, is probably required for cure. Although rare, reports of Brucella infection of prosthetic implants and devices have increased in the past decade. Brucellosis should be considered in the differential diagnosis of cardiac device infection in patients residing in or traveling to areas of endemicity.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Brucella melitensis / isolation & purification*
  • Brucellosis / diagnosis
  • Brucellosis / drug therapy*
  • Brucellosis / microbiology
  • Ciprofloxacin / therapeutic use
  • Defibrillators, Implantable / adverse effects*
  • Defibrillators, Implantable / microbiology
  • Device Removal
  • Doxycycline / therapeutic use
  • Follow-Up Studies
  • Humans
  • Male
  • Prosthesis-Related Infections / diagnosis
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / microbiology*
  • Retreatment
  • Risk Assessment
  • Treatment Outcome

Substances

  • Ciprofloxacin
  • Doxycycline