We have reported a case of cryptogenic liver abscess with bacteremia and septic pulmonary emboli due to Klebsiella ozaenae. This organism has not previously been reported as a cause of intra-abdominal infection and this is only the eighth reported case of bacteremia. K ozaenae is generally considered an opportunist of low virulence and a respiratory tract colonizer implicated in ozena (atrophic rhinitis). More information is required to understand the epidemiology and pathogenicity of human disease caused by K ozaenae.