Successful medical treatment of multiple brain abscesses due to Nocardia farcinica in a paediatric renal transplant recipient

Pediatr Nephrol. 2005 Aug;20(8):1186-8. doi: 10.1007/s00467-005-1978-6. Epub 2005 Jun 10.

Abstract

Brain abscesses caused by Nocardia are rare, but it is very important to detect and treat them early because the associated mortality is 3 times higher than that associated with other bacterial brain abscesses. This infection is prevalent among adults on long-term immunosuppressive therapy; we report the case of a male kidney transplant recipient aged 12.7 years who developed early multiple Nocardia-induced brain abscesses that were successfully treated with linezolid, a novel antibiotic therapy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetamides / therapeutic use*
  • Anti-Infective Agents / therapeutic use*
  • Brain Abscess / drug therapy*
  • Child
  • Humans
  • Kidney Transplantation / adverse effects*
  • Linezolid
  • Male
  • Nocardia Infections / drug therapy*
  • Oxazolidinones / therapeutic use*

Substances

  • Acetamides
  • Anti-Infective Agents
  • Oxazolidinones
  • Linezolid