Abstract
A 39-year-old man with Candida glabrata endophthalmitis was successfully treated with a 28-day course of intravenous caspofungin. Presence of underlying renal insufficiency and infection with a drug-resistant strain precluded use of amphotericin B or fluconazole. Intravitreal administration of antifungals and vitrectomy were not required. The role of caspofungin in Candida endophthalmitis is discussed.
MeSH terms
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Adult
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Antifungal Agents / therapeutic use
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Candida glabrata / drug effects
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Candida glabrata / isolation & purification*
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Candidiasis / diagnosis*
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Candidiasis / drug therapy
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Candidiasis / microbiology
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Caspofungin
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Drug Resistance, Multiple, Fungal
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Echinocandins
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Endophthalmitis / drug therapy*
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Endophthalmitis / microbiology*
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Endophthalmitis / pathology
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Humans
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Lipopeptides
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Male
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Peptides, Cyclic / therapeutic use*
Substances
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Antifungal Agents
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Echinocandins
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Lipopeptides
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Peptides, Cyclic
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Caspofungin