Nalidixic acid-resistant Salmonella enterica serotype Typhi presenting as a primary psoas abscess: case report and review of the literature

J Clin Microbiol. 2005 Feb;43(2):996-8. doi: 10.1128/JCM.43.2.996-998.2005.

Abstract

We report an unusual case of Salmonella enterica serotype Typhi presenting as a primary psoas abscess. The isolate tested susceptible to ciprofloxacin but resistant to nalidixic acid in vitro, a pattern associated with fluoroquinolone therapeutic failures. We review the literature for serovar Typhi psoas abscess in the absence of bacteremia and discuss the importance of identifying isolates with reduced susceptibility to fluoroquinolones.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anti-Infective Agents / pharmacology*
  • Drug Resistance, Bacterial*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Nalidixic Acid / pharmacology*
  • Psoas Abscess / microbiology*
  • Psoas Muscles / diagnostic imaging
  • Salmonella typhi / drug effects*
  • Salmonella typhi / isolation & purification
  • Tomography, X-Ray Computed
  • Typhoid Fever / microbiology*

Substances

  • Anti-Infective Agents
  • Nalidixic Acid