Aspergillus mediastinitis following orthotopic heart transplantation: case report and review of the literature

Transpl Infect Dis. 2004 Sep;6(3):129-31. doi: 10.1111/j.1399-3062.2004.00064.x.

Abstract

Bacterial mediastinitis after orthotopic heart transplantation (OHT) is well described in the literature. However, little information has been published on fungal mediastinitis in this population. We describe a man with Aspergillus fumigatus mediastinitis diagnosed 10 weeks after OHT. The patient was treated with voriconazole. The literature on Aspergillus mediastinitis is also reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Aspergillosis / diagnosis*
  • Aspergillosis / drug therapy
  • Aspergillus fumigatus / isolation & purification*
  • Drug Administration Schedule
  • Heart Transplantation*
  • Humans
  • Male
  • Mediastinitis / diagnosis*
  • Mediastinitis / microbiology*
  • Middle Aged
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / microbiology
  • Pyrimidines / administration & dosage
  • Pyrimidines / therapeutic use
  • Triazoles / administration & dosage
  • Triazoles / therapeutic use
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole