Fusarium solani endocarditis successfully treated with liposomal amphotericin B and voriconazole

Pediatr Infect Dis J. 2004 Nov;23(11):1059-61. doi: 10.1097/01.inf.0000143649.90952.41.

Abstract

Fungal infections caused by Fusarium in the immunocompromised host are highly resistant to all antifungal agents. Fusarium endocarditis is a rare and usually fatal disease. We report an immunocompromised child who survived Fusarium solani endocarditis despite the in vitro resistance of the organism to all available antifungal agents.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Amphotericin B / administration & dosage*
  • Antifungal Agents / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Drug Therapy, Combination
  • Endocarditis / diagnosis
  • Endocarditis / drug therapy*
  • Female
  • Follow-Up Studies
  • Fungemia / drug therapy*
  • Fungemia / microbiology
  • Fusarium / drug effects
  • Fusarium / isolation & purification
  • Humans
  • Immunocompromised Host
  • Infant
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / immunology*
  • Liposomes
  • Opportunistic Infections / diagnosis
  • Opportunistic Infections / drug therapy
  • Pyrimidines / administration & dosage*
  • Risk Assessment
  • Treatment Outcome
  • Triazoles / administration & dosage*
  • Voriconazole

Substances

  • Antifungal Agents
  • Liposomes
  • Pyrimidines
  • Triazoles
  • Amphotericin B
  • Voriconazole