Abstract
Cladophialophora bantiana is a dematiaceous fungus, associated with brain abscess in normal or immunosuppressed patients. We report a case of CNS infection in this agent unsuccessfully treated by surgery and various antifungal compounds including high doses of voriconazole (6 mg/kg bid). No adverse effects related to this compound were observed.
MeSH terms
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Aged
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Antifungal Agents / administration & dosage
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Brain Abscess / diagnosis
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Brain Abscess / drug therapy*
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Brain Abscess / surgery
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Central Nervous System Fungal Infections / diagnosis
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Central Nervous System Fungal Infections / drug therapy*
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Central Nervous System Fungal Infections / surgery
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Cladosporium / classification
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Cladosporium / drug effects*
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Combined Modality Therapy
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Disease Progression
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Fatal Outcome
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Fungemia / diagnosis
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Fungemia / drug therapy*
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Humans
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Male
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Pyrimidines / administration & dosage*
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Risk Assessment
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Severity of Illness Index
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Tomography, X-Ray Computed
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Treatment Failure
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Triazoles / administration & dosage*
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Voriconazole
Substances
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Antifungal Agents
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Pyrimidines
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Triazoles
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Voriconazole