Successsful voriconazole treatment of disseminated fusarium infection in an immunocompromised patient

Clin Infect Dis. 2003 Jul 15;37(2):311-3. doi: 10.1086/375842. Epub 2003 Jul 9.

Abstract

Fusarium infection is known to cause major morbidity and mortality in immunocompromised hosts. We report the successful treatment of disseminated Fusarium infection with skin manifestations in a severely neutropenic, immunocompromised host with voriconazole, a new second-generation triazole. Voriconazole might be an alternative therapy for patients with neutropenia who have fusariosis that is refractory or unresponsive to amphotericin B or its liposomal formulation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use*
  • Fusarium* / drug effects
  • Humans
  • Immunocompromised Host
  • Male
  • Mycoses / drug therapy*
  • Mycoses / physiopathology
  • Mycoses / transmission
  • Neutropenia / etiology
  • Pyrimidines / therapeutic use*
  • Treatment Outcome
  • Triazoles / therapeutic use*
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Amphotericin B
  • Voriconazole