Therapy for recurrent respiratory papillomatosis

Antivir Ther. 2002 Mar;7(1):1-9.

Abstract

Human papillomaviruses types 6 or 11 are aetiological agents of recurrent respiratory papillomatosis, a disease characterized by benign exophytic tumours usually on the vocal cords. Surgery debulks the tumours, but these growths generally recur at regular intervals. Adjunct medical treatments, aimed at containing the virus and growth of tumours, include indole-3-carbinol or its dimer diindolylmethane, interferon, photodynamic therapy and others. Preventive and therapeutic vaccines hold promise for eliminating the virus.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Cidofovir
  • Cytosine / analogs & derivatives*
  • Cytosine / therapeutic use
  • Humans
  • Interferons / therapeutic use
  • Laryngeal Neoplasms / therapy*
  • Lung Neoplasms / therapy*
  • Neoplasm Recurrence, Local / therapy*
  • Organophosphonates*
  • Organophosphorus Compounds / therapeutic use
  • Papilloma / therapy*
  • Papillomaviridae
  • Photochemotherapy
  • Vocal Cords*

Substances

  • Organophosphonates
  • Organophosphorus Compounds
  • Cytosine
  • Interferons
  • Cidofovir