Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin

Br J Clin Pharmacol. 2000 Oct;50(4):285-95. doi: 10.1046/j.1365-2125.2000.00261.x.

Author

Affiliation

¹ Unit of Geriatric Medicine, Drug and Therapeutics Committee, Etablissement Public de Santé Alsace Nord, BP 83, 67170 Brumath Strasbourg, France.

No abstract available

Publication types

Review

MeSH terms

Anti-Bacterial Agents / pharmacology*
Azithromycin / pharmacology
Clarithromycin / pharmacology
Clinical Trials as Topic
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System / metabolism*
Drug Interactions
Erythromycin / analogs & derivatives
Erythromycin / pharmacology
Humans
Macrolides
Mixed Function Oxygenases / metabolism*
Substrate Specificity

Substances

Anti-Bacterial Agents
Macrolides
dirithromycin
Erythromycin
Azithromycin
Cytochrome P-450 Enzyme System
Mixed Function Oxygenases
CYP3A protein, human
Cytochrome P-450 CYP3A
Clarithromycin