Abstract
Warts can be difficult to diagnose and to treat in the setting of human immunodeficiency virus (HIV) infection. A 37-year-old woman with a background of HIV presented with a large verrucous plaque involving her right foot. Human papillomavirus (HPV)-66 was identified in the lesional skin biopsy sample and in scrapings obtained from her cervix. The wart rapidly responded to topical cidofovir therapy. HPV-66 is a novel HPV type to be associated with verruca vulgaris. Topical cidofovir should be further investigated as an alternative treatment modality for verruca vulgaris.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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AIDS-Related Opportunistic Infections / drug therapy
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AIDS-Related Opportunistic Infections / pathology
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AIDS-Related Opportunistic Infections / virology*
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Administration, Topical
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Adult
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Antiviral Agents / administration & dosage*
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Biopsy
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Cidofovir
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Cytosine / administration & dosage
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Cytosine / analogs & derivatives*
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DNA, Viral / genetics
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Diagnosis, Differential
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Female
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Foot Dermatoses / drug therapy
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Foot Dermatoses / pathology
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Foot Dermatoses / virology*
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Humans
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Male
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Organophosphonates*
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Organophosphorus Compounds / administration & dosage*
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Papillomaviridae* / drug effects
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Papillomaviridae* / genetics
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Papillomavirus Infections / drug therapy
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Papillomavirus Infections / pathology
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Papillomavirus Infections / virology*
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Polymerase Chain Reaction
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Skin / pathology
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Skin / virology
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Warts / drug therapy
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Warts / pathology
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Warts / virology*
Substances
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Antiviral Agents
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DNA, Viral
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Organophosphonates
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Organophosphorus Compounds
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Cytosine
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Cidofovir