Dilemmas in drug development for tropical diseases. Experiences with praziquantel

Health Policy. 1998 Apr;44(1):1-18. doi: 10.1016/s0168-8510(98)00002-5.

Abstract

This article analyzes policies that affected the availability of praziquantel, the drug of choice for schistosomiasis. The study examines how interactions among four actors (pharmaceutical producers, international agencies, non-governmental agencies, and national governments) affected praziquantel availability in poor countries. It also examines trends in praziquantel prices over time in different markets. This analysis demonstrates that the discovery of an effective new drug does not necessarily result in access to the drug for disease sufferers--especially if those sufferers are poor people in poor countries. The article proposes measures to improve international systems for making new drugs available in poor countries.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthelmintics / economics
  • Anthelmintics / supply & distribution*
  • Anthelmintics / therapeutic use
  • Developing Countries
  • Drug Costs / trends
  • Drug Industry
  • Health Policy*
  • Health Services Accessibility / economics*
  • Health Services Accessibility / statistics & numerical data
  • Humans
  • International Cooperation
  • Poverty
  • Praziquantel / economics
  • Praziquantel / supply & distribution*
  • Praziquantel / therapeutic use
  • Private Sector
  • Public Sector
  • Schistosomiasis / drug therapy*
  • Tropical Medicine*

Substances

  • Anthelmintics
  • Praziquantel