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Table 1. Suggested Diagnostic Evaluation of the Febrile HIV-Infected Patient Based on CD4+

T-Cell Count


Table 2. Recommended Stool Sample Evaluation in the HIV-Infected Patient with Diarrhea 

Bacterial culture

Ova and parasite examination

Modified Acid-fast stain for Isospora belli, Cryptosporidium parvum, Cyclospora cayetanensis

Clostridium difficile toxin assay

Wright stain for fecal leukocytes

Consider colonoscopy in patients with persistent diarrhea and negative stool studies


Table 3. Recommended CSF Evaluation in the HIV-Infected Patient 

Opening pressure



Cell count: WBC with differential, RBC

Bacterial studies: Gram stain and culture; latex agglutination for antigen detection

Mycobacterial studies: AFB smear and culture

Fungal studies: KOH preparation; India ink stain; cryptococcal antigen; fungal culture



Table 4. Summary of Series Examining Fever of Unknown Origin in HIV-Infected Patients