Table 1: Time required for prevalence rates of resistance to reach 25% in hospitals.

 

Drug

Year Drug Introduced

Years to report of resistance

Years until 25% rate in hospitals

Years until 25% rate in the community

Penicillin

1941

1-2

6

15-20

Vancomycin

1956

40

?

?

Methicillin

1961

<1

25-30

40-50 (projected)

Chambers H. Emerging Infect Dis. 2001;7:179.


 

 

 

Figure 1: The sixth plaque of Egypt-the plague of boils (Exodus IV), 1483.

From the woodblocks of the Great Cologne Bible, 1483.

 

 

 

 

 


 

Figure 2: Increasing incidence of MRSA infection in the United States.

 


 

Figure 3: Chronologic evolution of resistant Staphylococcus aureus

 

                    Adapted from: CDCís 12 Steps to prevent antimicrobial resistance in hospitals. 

                   http://www.cdc.gov/drugresistance/healthcare/tools.htm#slides

 

 


 

Figure 4

 


 

    Figure 5: Community-acquired MRSA skin infection in a patient after obtaining a tattoo. 

    MMWR. 55(24):677-9. 2006. June 23

  


 

        Figure 6: Nosocomial necrotizing MRSA pneumonia with spontaneous right pneumothorax in ICU

        patient  (Photo courtesy of the author)