Monoxycarbolic acid
Streptococcus spp., Staphylococcus spp., H. influenzae, M. catarrhalis, Neisseria spp., P. multocida
Protein synthesis interruption by inhibition of isoleucine incorporation into growing bacterial protein chain.
Pharmacodynamics:
No data
Protein binding: 95%
Serum half-life: 20-35 minutes
Nares: local irritation, rhinitis
Skin: Rash, purities, headache
Other: taste alterations
Mupirocin Nasal Ointment (Parafin based) (1g)
Mupirocin Ointment (15, 30g)
Muprocin Ointment (Polyethylene glycol based) (22g)
Impetigo: Apply to affected area q 8 hours for 3 to 5 days
Nasal decolonization of MRSA: Apply to nares q 12h for 5 days
Disease state based dosing:
Renal failure: Dosing adjustments not necessary
Hepatic failure: Dosing adjustments not necessary
Contraindications/Warnings/Precautions:
Precautions:
No data available
Pregnancy:
Category B: No evidence of risk in humans but studies inadequate.
Patients should be monitored for symptoms of local irritation.
No laboratory parameters exist to monitor for efficacy or toxicity
Brand names/Manufacturer: