Table 1. Susceptibility of geohelminths to diethylcarbamazine (37)
|
Species |
Cure rate (%) |
Egg reduction Rate (%) |
|
Ascaris lmbricoides |
31 |
77 |
|
26 |
36 |
|
|
Trichuris trichuria |
77 |
86 |
Table 2. Susceptibility of various lifecycle stages of filarial parasites to diethylcarbamazine
|
Species |
Microfilariae |
Adult worms |
Infective larvae |
|
Wuchereria bancrofti |
+++ |
+ |
? + |
|
Brugia malayi |
+++ |
+ |
+ |
|
Loa loa |
+++ |
+ |
++ |
|
Onchocerca volvulus |
+++ |
- |
- |
Figure 1. Chemical structure of diethylcarbamazine