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Leishmania species (Leishmaniasis)

 

 

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Tables and Figures

Table 1: Drugs for the Treatment of Visceral Leishmaniasis [Download PDF]

Table 2: Adverse events during antimony treatment as reported in different studies 

Table 3: Results of treatment of mucosal leishmaniasis with pentavalent antimony alone or pentavalent antimony plus allopurinol in one study. 

 

Vignettes

Life Cycle of Leishmania species

Review Article: Cutaneous Leishmaniasis. Reithinger, R., Dujardin, J., Pirmez, C., Alexander, B. and Brooker, S. The LANCET Infectious Diseases 2007; Vol.7, Issue 9, 581-596.

Antinori S, Cascio A, et al. Leishmaniasis Among Organ Transplant Recipients. Lancet Infect Dis. 2008 Mar;8:191-9.

Arevalo J, et al.  Influence of Leishmania (Vianna) Species on the Response to Antimonial Treatment in Patients with American Tegumentary Leishmaniasis. JID 2007;195:1846-1851.

Sundar S, Jha TK, Thakur CP, Sinha PK, Bhattacharya SK.  Injectable paromomycin for visceral leishmaniasis in India.  New Engl J Med 2007;356:2571-2581.

Sundar S, Chakravarty J, Rai VK, Agrawal N, Singh SP, Chauhan V, Murray HW.  Amphotericin B Treatment for Indian Visceral Leishmaniasis: Response to 15 Daily versus Alternate-Day Infusions.  Clin Infect Dis 2007;45:556-561.

Pedras MJ, et al.  Comparative evaluation of direct agglutination test, rK39 and soluble antigen ELISA and IFAT for the diagnosis of visceral leishmaniasis.  Trans R Soc Trop Med Hyg 2008 Feb;102(2):172-8.

Paniz Mondolfi AE, et al. Successful Treatment of Old World Cutaneous Leishmaniasis Caused by Leishmania infantum with Posaconazole. Antimicrob Agents Chemother 2011;55:1174-1776.

Kim DH, et al. Is Paromomycin an Effective and Safe Treatment against Cutaneous Leishmaniasis? A Meta-Analysis of 14 Randomized Controlled Trials. PLoS Negl Trop Dis 2009;3(2): e381.

Wasan KM, Wasan EK, et al. Highly Effective Oral Amphotericin B Formulation against Murine Visceral Leishmaniasis. J Infect Dis. 2009 Aug 1;200:357-360.

Potera C.  Heart Drug Helps to Beat Chagas, Leishmania Parasites.  Microbe 2009;4:490-491.

Sousa AQ, Pearson R. Drought, smallpox, and emergence of Leishmania braziliensis in northeastern Brazil. Emerg Infect Dis. 2009 Jun;15:916-21.

Hervás JA, et al. Old World Leishmania infantum Cutaneous Leishmaniasis Unresponsive to Liposomal Amphotericin B Treated With Topical Imiquimod. Pediatr Infect Dis J. 2011 Aug 8. [Epub ]

 

Authors

  Piet A. Kager, M.D., Ph.D.

 

 

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