Table 1. Taxonomy of Burkholderia cepacia Complex Species.

Species Former genomovar designation

B. cepacia I

B. multivorans II

B. cenocepacia III

B. stabilis IV

B. vietnamiensis V

B. delosa VI

B. ambifaria VII

B. anthina VIII

B. pyrrocinia IX

Table 2: Summary of Data From Selected Studies of the In Vitro Activity of Selected Antimicrobial Agents For Isolates of B. cepacia Complex from Non-Cystic Fibrosis and Cystic Fibrosis Patients.

	Strains from Non-Cystic Fibrosis Patients				Strains from Cystic Fibrosis Patients
		MIC (mg/mL)				MIC (mg/mL)
Agent	Number tested	MIC₅₀	MIC₉₀	MIC Range	Number tested	MIC₅₀	MIC₉₀	MIC Range	Ref
Ceftazidime	29	8	16	<0.03-16	26	8	>64	2->64	55
	110	2	4	0.06->128	20	8	32	1->128	33
	36	4	16	1-128	--				39
	--				66	8	32	1->64	8
	--				34	4	16	0.5->64	28
Cefipime	36	>128	>128	1->128	--				39
Chloramphenicol	110	16	32	1-128	20	16	64	2->128	33
Ciprofloxacin	29	2	16	<0.03-64	26	2	64	0.25-64	55
	110	1	2	<0.06-128	20	8	128	0.25-128	33
	36	1	4	0.25-64	--				39
	52	2	>2	<0.015->2	--				7
	--				66	16	64	4->64	8
	--				34	4	16	<0.06-16	28
Gatifloxacin	52	2	16	0.06->16					7
Imipenem	29	8	32	<0.03->64	26	16	>64	1->64	55
	36	8	128	1-128	--				39
	--				66	16	64	4->64	8
	--				34	16	32	2->64	28
Levofloxacin	29	4	16	<0.03-32	26	2	16	0.25-64	55
	52	2	>4	<0.5->4					7
Meropenem	110	2	4	<0.06-16	20	2	16	1-16	33
	--				66	4	8	1-16	8
Minocycline	36	1	4	<0.06-8	--				39
Ofloxacin	29	4	32	<0.03-32	26	2	32	0.5->64	55
	52	4	>4	0.12->4	--				7
Piperacillin	29	8	32	2->64	26	8	>64	4->64	55
	36	128	>128	2->128	--				39
	--				66	32	>128	2->128	8
Piperacillin- tazobactam	29	8	32	2->64	26	8	>64	4->64	55
Temocillin	--				66	8	32	2-64	8
Trimethoprim- sulfamethoxazole	110	4	32	4-128	20	32	128	4->128	33
	29	4	16	0.25->64	26	32	>64	4->64	55
	36	0.5	4	<0.06-8	--				39
	--				66	2	8	0.2-8	8

Strains from Non-Cystic Fibrosis Patients

Strains from Cystic Fibrosis Patients