Drug formulation (manufacturer)

Common names

Activity

Doses (mg)

Half-life  (hrs)

Side-effects

Active chemical

Date introduced

Remark

Levamisole    (ICI;            Janssen;    Zeneca)   

Ketrax,  Decaris

Excellent

40-150* single dose oral

4

Mild nausea & vomiting

Imidazothiazole

1968

Drug   of     choice

Mebendazole (Janssen)

Vermox, Pentelmin

Very good

100  2 ice daily for 3 days, oral

Transient abdominal pain & diarrhoea

Benzimidazole carbamate

1971

Albendazole (Smith-Kline & French)

Zentel

Very good

400 single  dose, oral

Abdominal discomfort, headache

Benzimidazole carbamate

1979

Pyrantel (Pfizer)

Combantrin

Very good

5-10mg\kg to max. 19g single dose oral

Mild nausea, abdominal cramps, vomiting & diarrhoea

Trtrahydropyrimidine

1966

Piperazine (Elixir & others)

Antezin (& others)

Good

40 single oral

Diplopia, myoclonus and mild renal  dysfunction in the elderly

Diethylenediamine