www.antimicrobe.org

[Start Page] [Microbes] [Antimicrobial Agents] [HIV Clinical Manual] [Feedback] [Logout]

Plasmodium species (Malaria)

 

Read the Chapter

Sliding Table of Contents on the left of the screen

Plasmodium species (Malaria)

Prevention of Malaria in Travelers

 

Tables and Figures

Plasmodium species (Malaria)

Table 1. Currently Available Antimalarial Drugs

Table 2. Dosing Schedule for Artesunate plus Amodiaquine

Table 3. Dosing Schedule for Artesunate plus Sulfadoxine-Pyrimethamine

Table 4. Dosing Schedule for Artemether-Lumefantrine

Table 5. Dosing Schedule for Artesunate plus Mefloquine

Table 6. Recommendations on the Treatment of Falciparum Malaria in Non-immune Travellers

Table 7. Antimalarial Treatment of Severe Malaria

Table 8. Treatment of Uncomplicated Vivax and Ovale Malaria.

Table 9. Treatment of Malaria in Pregnancy

Table 10. Management of Falciparum Malaria in Neonates

Table 11. Recent WHO Definitions of Treatment Failure

Table 12Overview of WHO Criteria for Signs of Severity

 

Prevention of Malaria in Travelers

Table 1: Recommended Prophylactic Regimens according to Chloroquine Resistance Patterns and Sites of Action

Table 2: Recommendations for Travelers to Malaria Risk Countries in the Americas and the Caribbean

Table 3: Recommendations for Traveler’s to Malaria Risk Countries in Africa

Table 4: Recommendations for Traveler’s to Malaria Risk Countries in Eastern Europe and the Independent States of the former Soviet Union

Table 5: Recommendations for Traveler’s to Malaria Risk Countries in Asia (Including the Middle East, Indian Subcontinent, and Southeast Asia)

Table 6: Recommendations for Traveler’s to Malaria Risk Countries in Oceania (Australia and the South Pacific Islands)

 

Vignettes

Life cycle of Plasmodium species

CDC Report, 2007. Artesunate Available for Treatment of Severe Malaria in the U.S.

White NJ, Day NPJ, Dondorp AM, Anstey N.  Letter to the Editor. UK recommendations for severe malaria are worrying.  BMJ 2007;10:334-490].

Lacroix et al.: Malaria Infection Increases Attractiveness of Humans to Mosquitoes. PLoS Biology, September 2005.

Cox-Singh J, et al. Plasmodium knowlesi malaria in humans is widely distributed and potentially life threatening. Clin Infect Dis. 2008 Jan 15;46(2):165-71.

Greenhouse B et al. Decreasing Efficacy of Antimalarial Combination Therapy in Uganda is Explained by Decreasing Host Immunity Rather than Increasing Drug Resistance.J Infect Dis. 2009 Mar 1;199(5):758-65.

Boggild AK, et al.  Use of Peroxisome Proliferator-Activated Receptor γ agonists as Adjunctive Treatment for Plasmodium falciparum Malaria: A Randomized, Double-Blind, Placebo-Controlled Trial.  Clin Infect Dis 2009;49:841-849.

Sykes, A, et al.  Azithromycin plus Artesunate versus Artemether-Lumefantrine for Treatment of Uncomplicated Malaria in Tanzanian Children: A Randomized Controlled Trial. Clin Infec Dis 2009;49:1195-1201.

Specter M.  The Mosquito Solution. Can genetic modification eliminate a deadly tropical disease?  The New Yorker July 9 & 16, 2012.

Review Article: Franco-Paredes C and Santos-Preciado JI. Problem pathogens: prevention of malaria in travellers. Lancet Infect Dis 2006;6:139-49.

Review Article:  Lallo DG, et al, for the HPA Advisory Committee on Malaria Prevention in UK Travellers.  J Infec 2007;54:111-121.

Mege JL, Meghari S, Honstettre A, Capo C, Raoult D The Two faces of interleukin 10 in human infectious diseases.  Lancet Infectious Diseases 2006:7;557-569.

Review Article:  Efflux Pumps as a Mechanism of Antimicrobial Resistance. 2008

Review Article: Ladhani, S., Aibara, R., Riordan, F., and Shingadia, D. Imported Malaria in Children: A Review of Clinical Studies. The LANCET Infectious Diseases 2007; Vol.7, Issue 5, 349-357.

Review Article:  Ward S.A., et al.  Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance.  Lancet Infectious Diseases 2007;7(2):136-144.

Review Article:  Rogerson S.J., et al.  Malaria in pregnancy: pathogenesis and immunity.  Lancet Infectious Diseases 2007;7(2): 105-115.

Peripheral blood film: Ring forms of Plasmodium falciparum

Benedek TG: History of Malaria Chemotherapy.

Grizzard M and Grizzard M. The Source of Quinine. Clin Infect Dis. 2009 Jun 1;48.

Tognotti, E.  Program to Eradicate Malaria in Sardinia, 1946-1950: Communism, DDT toxicity and the economics of malaria. Emerging Infect Dis. 2009;15(9): 140-1466.

 

 

Authors

  Nicholas J. White, M.D., Arjen M. Dondorp, M.D., Daniel H. Paris, MD,  Carlos Franco-Paredes, M.D., MPH,  

 

 

 

www.antimicrobe.org

[Start Page] [Microbes] [Antimicrobial Agents] [HIV Clinical Manual] [Feedback] [Logout]