Table 4. Contraindications to treatment with Interferon alfa/Ribavirin.   

 

 

Interferon alfa

Ribavirin

Combination Interferon alfa and Ribavirin

Absolute

Active suicidal behavior

Autoimmune hepatitis

Hypersensitivity to Interferon alfa

Pregnancy

Same as individual drugs

Relative

Active autoimmune disease (other than autoimmune hepatitis)

Depression (stabilize before starting treatment)

 

Anemia

Renal failure

Same as individual drugs

Decompensated cirrhosis